They were once feared and forced to live in the shadows. But as modern society grew more enlightened, human beings began to realize that monsters like succubi, dullahans, and vampires deserve public services as much as anyone. Still, a girls' high school for monsters? It sounds like a nightmare, but for one man it's a dream job. Tetsuo has always been fascinated by "demi-humans," and a job opening for a biology teacher at this school is his chance to see them firsthand! Call them "demis"! Vampires, dullahans, succubi, snow women. These are just a few of those beings once known as "demi-humans," and high school Biology teacher Testsuo Takahashi has always wanted to meet them. He gets his chance when the new term starts, and there are four "demis" in his school! Join the caring, bumbling Tetsuo in his quest to get to know these adorable monster girls, while helping them navigate the highs and lows of high school!