Isolation and Molecular Characterization of Circulating Tumor Cells

Name: Isolation and Molecular Characterization of Circulating Tumor Cells
SKU: 28328087
Price: 484.99 AUD
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Format:

Paperback / softback

Series:

Advances in Experimental Medicine and Biology

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Description

Numerous studies have shown that elevated levels of circulating tumor cells (CTCs) in blood of cancer patients are associated with poor response to treatment and inferior survival probabilities. Despite this clinical significance, the molecular biology of CTCs remains poorly understood. The paucity in molecular information can be attributed to the tremendous technical challenges involved in isolating these extremely rare cells. Recent technological advancements in rare-cell technology, however, have allowed for the reliable enrichment and isolation of CTCs. Consequently, the use of recently developed molecular approaches —e.g., multiplexed QPCR, microarray, and next generation sequencing analyses— to profile CTCs have provided novel insights into the molecular makeup of these tumor cells. This book discusses approaches for enrichment and isolation of CTCs as well as recent advances in comprehensive molecular profiling of CTCs using cutting-edge omics technology.

Release date Australia

August 2nd, 2018

Audience

Professional & Vocational

Contributors

Edited by John W. Park
Edited by Mark Jesus M. Magbanua

Edition

Softcover reprint of the original 1st ed. 2017

Illustrations

15 Illustrations, color; 27 Illustrations, black and white; XVI, 301 p. 42 illus., 15 illus. in color.

Pages

301

Series

Advances in Experimental Medicine and Biology

ISBN-13

9783319857879

Product ID

28328087

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Isolation and Molecular Characterization of Circulating Tumor Cells

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