Mary Lou and the Red Hat Mafia continues the adventures of Mary Lou Farmington as she attempts to escape suspicion in the police investigation into the disappearance of her son-in-law. Thereas just one problemasheas the one who shot him and her sister and bridge club friends are the ones who covered it up. To make matters worse, new events suggest that he may still be alive and out for revenge. The memorable cast of characters from Mary Louas Bridge and Murder Club returns as a new nemesis arrives on the scene and puts Mary Lou, Alice, Edna and Victoria in a predicament more dire than ever before. Pyromania, murder and hilarity ensue as the ladies try to get themselves out of trouble once again. Mary Lou realizes that sheall have to go to great lengths to save herself, her friends and her daughteraeven if it means joining the townas new Red Hat Society.