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Molecular Basis of Sex Hormone Receptor Function
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Molecular Basis of Sex Hormone Receptor Function

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Description

How sex hormone receptors and all the other members of the nuclear receptor superfamily do such a remarkable job has fascinated scientists for decades. A series of discoveries in the past few years has dramatically enlightened our understanding of the molecular mechanisms that govern nuclear receptor action. The elucidation of the 3D structures of several nuclear receptor ligand binding domains in the presence of agonists or antagonists has provided an allosteric concept of ligand action, and the discovery of a plethora of ligand-dependent protein interactions has linked this transconformation with the ability of nuclear receptors to act as transcriptional activators and repressors and the enzymatic modification of chromatin and factors of the basal transcriptional machinery.
Release date Australia
October 3rd, 2013
Audience
  • Professional & Vocational
Contributors
  • Edited by Hinrich Gronemeyer
  • Edited by Karsten Parczyk
  • Edited by Ulrike Fuhrmann
Edition
Softcover reprint of the original 1st ed. 1998
Illustrations
58 Illustrations, black and white; XIV, 238 p. 58 illus.
Pages
238
Dimensions
148x210x13
ISBN-13
9783662036914
Product ID
21698687

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