Provides an update on the use of the molecular biology of the lung and their diseases.
Table of Contents
Application of transgenic and gene-targeted mice to dissect mechanisms of lung disease, Steven D. Shapiro. Emphysema: models of genetic emphysema - the C57B1/6J mice and their mutants - tight-skin, pallid and biege, Guiseppe Lungarella et al; x1-antitrypsin deficiency, R.A. Stockley; recombinant SLPI - emphysema and asthma, J. Stolk and P.S. Hiemstra; elastase inhibitors in the lung - expression and functional relationships, Jean-Michael Sallenave et al; regulation of neutrophil proteases, Anne B. Sturrock and John R. Hoidal; control of connective tissue genes, Joel Rosenbloom. Infection: genetic models of bacterial lung infection, Timothy J. Mitchell; genetics of bacteria - role in pathogenesis of infection of the respiratory tract infections, Neil W. Schluger; cystic fibrosis, Uta Griesenbach et al; respiratory bacterial infections in patients with cystic fibrosis - pathogenicity and implications for serine proteinase inhibitor therapy, Gerd Doring.
