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Molecular Toxicology Protocols
Molecular Toxicology Protocols
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Molecular Toxicology Protocols

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Description

A collection of cutting-edge techniques for analyzing genotoxic exposure and detecting the resulting biological effects-including endogenous metabolites-up to and including the development of cancer. The authors emphasize analytical methods that can be specifically applied to human populations and patients. Among the applications detailed are the analysis of interactions between such cellular macromolecules as DNA and proteins and chemical and physical agents, the assessment of medically relevant toxicity, and the characterization of genetic alterations induced in transgenic animals by in vivo systems. There are also methods for the analysis of genotoxic exposure during gene expression, of cytotoxicity caused by the induction of apoptosis, of genetic alterations in reporter genes and oncogenes, early (premalignant) detection of altered oncogenes, and of individual variation in biotransformation and DNA repair capacity.
Release date Australia
September 21st, 2011
Audience
  • Professional & Vocational
Contributors
  • Edited by Phouthone Keohavong
  • Edited by Stephen G. Grant
Illustrations
XIV, 489 p.
Pages
489
Dimensions
155x235x25
ISBN-13
9781617373473
Product ID
10817545

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