One in ten newborns worldwide suffers from preterm birth, a serious health problem. It is impossible to overstate the significance of comprehending preterm birth. Preterm birth has a significant impact on families, healthcare systems, and society as a whole, and it is a leading cause of infant death and disability. However, many preterm infants can live healthy lives with the right medical care. Preterm birth's causes, risk factors, symptoms and signs, diagnosis, treatment options, prevention, and coping strategies are all covered in detail in this guide. Families will gain a better understanding of the difficulties associated with preterm birth and the steps they can take to ensure their baby has the best possible outcome thanks to the information in this guide. This guide can also be used by healthcare professionals to educate families and give them the support they need during this trying time.