Non-Fiction Books:

Progress in DNA Methylation Research

Format

Hardback

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Progress in DNA Methylation Research
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Description

DNA methylation is a type of chemical modification of DNA that can be inherited without changing the DNA sequence. As such, it is part of the epigenetic code and is the most characterised epigenetic mechanism. DNA methylation involves the addition of a methyl group to DNA -- for example, to the number 5 carbon of the cytosine pyrimidine ring. DNA methylation is probably universal in eukaryotes. In humans, approximately 1% of DNA bases undergo DNA methylation. In adult somatic tissues, DNA methylation typically occurs in a CpG dinucleotide context; non-CpG methylation is prevalent in embryonic stem cells.In plants, cytosines are methylated both symmetrically (CpG or CpNpG) and asymmetrically (CpNpNp), where N can be any nucleotide. The methylation status of specific cytosines can be determined using methods based on bisulfite sequencing. This book presents leading-edge research advances in the field.
Release date Australia
November 1st, 2007
Contributor
Edited by Hans P. Neumann
Country of Publication
United States
Illustrations
tables & charts
Imprint
Nova Science Publishers Inc
Pages
256
ISBN-13
9781600217227
Product ID
2320211

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