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Protein Folding, Misfolding, and Disease

Methods and Protocols
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Description

Protein misfolding is a key feature of many disorders in humans, given that over twenty proteins are known to misfold and cause disease.  In Protein Folding, Misfolding, and Disease: Methods and Protocols, experts in the field present a collection of current methods for studying the analysis of protein folding and misfolding, featuring strategies for expressing and refolding recombinant proteins which can then be utilized in subsequent experiments. This detailed volume also covers methods for analyzing the formation of amyloid, protocols for determining the size and structure of native and misfolded proteins, as well as specific examples of where misfolded proteins can be examined using state-of –the-art technologies. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Up to date and authoritative, Protein Folding, Misfolding, and Disease: Methods and Protocols offers researchers the tools necessary to move ahead in this vital field.
Release date Australia
August 23rd, 2016
Audience
  • Professional & Vocational
Contributors
  • Edited by Andrew F Hill
  • Edited by Kevin J Barnham
  • Edited by Roberto Cappai
  • Edited by Stephen P Bottomley
Edition
Softcover reprint of the original 1st ed. 2011
Illustrations
X, 249 p.
Pages
249
ISBN-13
9781493956890
Product ID
28501215

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