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Retinal Degenerations

Mechanisms and Experimental Therapy
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Description

The topics in this volume explore the etiology, cellular mechanisms, epidemiology, genetics, models and potential therapeutic measures for the blinding diseases of retinitis pigmentosa and age-related macular degeneration. Special focus is highlighted in the areas of Mechanisms of Photoreceptor Degeneration and Cell Death (extremely important because very little is known how or why photoreceptors die in these diseases, despite an abundance of genetic information), Age-Related Macular Degeneration (with several novel approaches to its analysis), Usher Syndrome (the most severe form of retinitis pigmentosa, which includes an early or congenital loss of hearing along with blindness), and Gene Therapy. In addition, the section on Basic Science Related to Retinal Degeneration is particularly strong with several laboratories reporting on new discoveries in the area of outer segment phagocytosis, a key component of photoreceptor-retinal pigment epithelial cell interactions in normal and degenerating retinas.
Release date Australia
February 11th, 2013
Audience
  • Professional & Vocational
Contributors
  • Edited by Joe G. Hollyfield
  • Edited by Matthew M Lavail
  • Edited by Robert E. Anderson
Edition
Softcover reprint of the original 1st ed. 2003
Illustrations
XVI, 467 p.
Pages
467
Dimensions
178x254x25
ISBN-13
9781461349099
Product ID
21700304

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