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Targeted Protein Degradation

Methods and Protocols
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Description

This volume contains a collection of innovative techniques for studying targeted protein degradation. Chapters guide readers through heterobifunctional proteolysis-targeting chimeras (PROTACs) approaches, E3 ligase, E3 ligase-induced ubiquitylation, proteomic approaches, novel degrader molecules, molecular glue, and stabilize binding interaction between a target and E3 ubiquitin ligase. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.   Authoritative and cutting-edge, Targeted Protein Degradation: Methods and Protocols aims to ensure successful results in this emerging field of drug discovery.  
Release date Australia
August 26th, 2021
Audience
  • Professional & Vocational
Contributors
  • Edited by Angela M. Cacace
  • Edited by Christopher M. Hickey
  • Edited by Miklos Bekes
Edition
1st ed. 2021
Illustrations
50 Illustrations, color; 17 Illustrations, black and white; XI, 351 p. 67 illus., 50 illus. in color.
Pages
351
ISBN-13
9781071616673
Product ID
35957628

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