Taurine 4

Name: Taurine 4
SKU: 21689636
Price: 539.99 AUD
Availability: InStock

Taurine and Excitable Tissues

Format:

Paperback / softback

Series:

Advances in Experimental Medicine and Biology

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Description

Mitochondria from mammalian tissues possess an elaborate system for 2+ 2+ transporting Ca across their inner membrane which consists of Ca import, 2+ via the Ca uniporter, in response to the mitochondrial membrane 2+ + potential ?? and of Ca release by an antiport system in exchange for H + 9,23 or Na (see Fig. l) . Because the uniporter is dependent upon the external 2+ 2+ 2+ 2+ Ca concentration ([Ca ]), mitochondria accumulate Ca until the [Ca ] o o 2+ decreases to the level at which the uniporter activity balances the Ca efflux. 2+ The [Ca ] at which the uniporter and efflux activities are equal is defined o the “setpoint” andcorresponds to values between 0.3-3µM. 2+ Figure 1. The Ca transport system of the inner membrane of mammalian mitochondria. U, + 2+ + + uniporter. I, Na -independent efflux mechanism or Ca /2H exchanger. D, Na -dependent 2+ + efflux mechanism or Ca /2Na exchanger. PTP, permeability transition pore. FP, 11 flavoprotein. ?? membrane potential. ? pH gradient. Adapted from .

Release date Australia

March 12th, 2013

Audience

Professional & Vocational

Contributors

Edited by Giampietro Sgaragli
Edited by Keith F. Tipton
Edited by Laura Della Corte
Edited by Ryan J. Huxtable

Illustrations

XXIV, 652 p.

Pages

652

Series

Advances in Experimental Medicine and Biology

Dimensions

155x235x35

ISBN-13

9781475773422

Product ID

21689636

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