This exciting new reference brings you information about the most controversial pulmonary challenges you face in your practice. The book confidently tackles these subjects and gives seasoned advice on the latest diagnostic and treatment strategies using evidence-based medicine wherever possible. It gives you the latest information you need to keep pace with the fast-paced, dynamic environment of neonatology.

Table of Contents

Section 1: Lung Development 1. Molecular Basis for Normal and Abnormal Lung Development. Martin Post, PhD Martin Rutter, HBSC 2. Hereditary Disorders of Alveolar Homeostasis in the Newborn. Jeffrey Whitsett, MD Timothy Weaver, PhD 3. Growth and Development of the Lung Circulation Mechanisms and Clinical Implications Steve Abman, MD Christopher Baker, MD Vivek Balasubramania, MD 4. Surfactant: The Basis for Clinical Treatment Strategies Alan Jobe, MD, PhD Section 2: Injury in the Developing Lung 5. Susceptibility of the Immature Lung to Oxidative and Mechanical Injury. Jaques Belik, MD, FRCPC 6. Inflammation/Infection: Effects on the Fetal/Newborn Lung Alan Jobe, MD, PhD Suhas Kallapur, MD Timothy J.M. Moss, PhD 7. Lung Fluid Balance During Development and in Neonatal Lung Disease Richard Bland, MD David P. Carlton, MD Lucky Jain, MD 8. Role Of Inflammation In The Pathogenesis Of Acute And Chronic Neonatal Lung Disease Christian Speer, MD, FRCPE 9. New Developments In The Presentation, Pathogenesis, Epidemiology And Prevention Of BPD Ilene Sosenko, MD Eduardo Bancalari, MD 10. What Is The Evidence For Drug Therapy In The Prevention And Management Of Bronchopulmonary Dysplasia Henry Halliday, MD, FRCP, FRCPE Conner O'neill, MB, BCH, BAO, MRCPCH 11. Definitions and Predictors of Bronchopulmonary Dysplasia. Michele Walsh, MD, MS 12. New Developments In The Pathogenesis And Management Of Neonatal Pulmonary Hypertension. Judy Aschner, MD Candice Fike, MD 13. Impact of Perinatal Lung Injury in Later Life Lex W. Doyle, MD, FRACP Peter J. Anderson, PhD Section 3: Management of Respiratory Failure Unnumbered Section: Oxygen 14. The Oxygen Versus Room Air Controversy for Neonatal Resuscitation Peter Fowlie, MB, ChB, MSc, DRCOG, MRCGP, FRCPCH Dr. Hannah Shore, MB, CHB, MRCPCH 15. Optimal Levels Of Oxygenation In Preterm Infants: Impact On Short And Long-Term Outcomes. Win Tin, MB, BS, FRCP, FRCPCH Samir Gupta, MB, BS, MD, MRCP, FRCPCH Unnumbered Section: Mechanical Respiratory Support 16. Non Invasive Respiratory Support: An Alternative To Mechanical Ventilation In Preterm Infants. Peter Davis, MD, FRACP Colin Morley, MD 17. High Frequency Ventilation in Neonatal Respiratory Failure. Waldemar Carlo, MD Ulrich Thome, MD 18. New Modalities of Mechanical Ventilation in the Newborn Eduardo Bancalari, MD Nelson Claure, PhD 19. Role of Pulmonary Function Testing in the Management of Neonates on Mechanical Ventilation Tilo Gerhardt, MD Nelson Claure, PhD Section 4: Respiratory Control and Apnea of Prematurity 20. Neonatal Respiratory Control and Apnea of Prematurity Richard J. Martin, MBBS, FRACP Oded Mesner, MD Juliann M. Di Fiore, BSEE 21. Strategies For Prevention Of Apneic Episodes In Preterm Infants: Are Respiratory Stimulants Worth The Risk? Barbara Schmidt, MD, MSc Dirk Bassler, MD, MSc