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Diverse Effects of Hypoxia on Tumor Progression

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Description

Hypoxia, defined as reduced oxygen tension, is a common physiological phenomenon in both normal embryonic development and malignancy progression. Although severe hypoxia is generally toxic for both normal tissue and tumors, neoplastic cells gradually adapt to prolonged hypoxia though additional genetic and genomic changes with a net result that hypoxia promotes tumor progression and therapeutic resistance. Hypoxia promotes cancer progression by regulating various aspects of cancer biology, including radiotherapy resistance, metabolism, angiogenesis and invasion/migration
Release date Australia
November 5th, 2012
Audience
  • Professional & Vocational
Contributor
  • Edited by M. Celeste Simon
Illustrations
X, 146 p.
Pages
146
Dimensions
155x235x13
ISBN-13
9783642264849
Product ID
20930224

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